Influence of paraffin oil on behavior of gel-based drug carrier: molecular modeling study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F12%3A86084643" target="_blank" >RIV/61989100:27640/12:86084643 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Influence of paraffin oil on behavior of gel-based drug carrier: molecular modeling study
Original language description
Molecular modeling is nowadays routinely employed in many branches of science and pharmaceutical chemistry is not an exception. This modeling study was focused on behavior of amphiphilic gels mixture serving as a carriers of drug cyclosporine A (CsA) andthe main aim was to find whether the contact with small amount of paraffin oil during the production can affect this behavior. Two systems were studied in Accelrys Materials Studio modeling environment: (1) pure gel-based CsA carrier and (2) gel-based drug carrier with small amount of paraffin oil added (~ 4 wt.%). The attention has been paid mainly to the homogeneity of CsA/gel clusters, pervasion of water into clusters and energy characteristics of clusters. It was found that the presence of small amount of paraffin oil does not affect the behavior of carrier.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/ED1.1.00%2F02.0070" target="_blank" >ED1.1.00/02.0070: IT4Innovations Centre of Excellence</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON 2012 : 4th international conference : conference proceedings : October 23rd-25th 2012, hotel Voroněž I, Brno, Czech Republic, EU
ISBN
978-80-87294-35-2
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
564-568
Publisher name
Tanger
Place of publication
Ostrava
Event location
Brno
Event date
Oct 23, 2012
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
000333697100103