METAL AND CARBON-BASED PARTICLES / CLUSTERS IN THE PERIPHERAL T - CELL LYMPHOMA IN THE LUNGS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F15%3A86099737" target="_blank" >RIV/61989100:27640/15:86099737 - isvavai.cz</a>
Alternative codes found
RIV/61989100:27740/15:86099737
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
METAL AND CARBON-BASED PARTICLES / CLUSTERS IN THE PERIPHERAL T - CELL LYMPHOMA IN THE LUNGS
Original language description
Submicron particles occurring in the environment are of natural origin, but are also formed by anthropogenic activities as secondary products. The source of these submicron particles are e.g. energy industries, ore processing, cosmetic and pharmaceutical industries, smoking, transportation, etc. Chemical composition of these particles from single sources is not precisely known. Due to their size (<1 mu m) they can be easily inhaled and thus enter deep respiratory tract into the lungs. Depending on their size and chemical composition they may have the ability to induce oxidative stress in cells, which lead to damage to the body eventually. The paper addresses occurrence of unspecified peripheral T-cell lymphoma in a 74-year-old male patient, non-smoker, previously working in metal rollers worker. This case was evaluated from the pathological point of view, together with a detection of submicron particles/clusters in the sample of the tumor tissue. Histologically the tumor was in lung tissue inaccurately bounded with diffusely growing medium sized to large lymphoid elements having nuclei of irregular size and shape and with one or multiple nucleoli with prominent mitotic activity. Dark pigment was also dispersed in the tissue during examination by light microscopy at high magnification under polarized light and also foreign particles probably of metallic character were observed. Experimental method used included scanning electron microscopy with energy dispersive spectroscopy (SEM -EDX) and Raman microspectroscopy. SEM - EDX revealed presence of particles/clusters in sizes <500 nm based mainly on iron. Occurrence of iron particles namely siderite (FeCO3) was confirmed by Raman microspectroscopy. Moreover the tumor tissue was identified to contain carbon black and graphite-based particles.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
DN - Environmental impact on health
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LO1203" target="_blank" >LO1203: Regional Materials Science and Technology Centre - Feasibility Program</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON 2015: 7th international conference : proceedings of abstracts
ISBN
978-80-87294-59-8
ISSN
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e-ISSN
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Number of pages
558
Pages from-to
553
Publisher name
Tanger
Place of publication
Ostrava
Event location
Brno
Event date
Oct 14, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000374708800097