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METAL AND CARBON-BASED PARTICLES / CLUSTERS IN THE PERIPHERAL T - CELL LYMPHOMA IN THE LUNGS

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F15%3A86099737" target="_blank" >RIV/61989100:27640/15:86099737 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989100:27740/15:86099737

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    METAL AND CARBON-BASED PARTICLES / CLUSTERS IN THE PERIPHERAL T - CELL LYMPHOMA IN THE LUNGS

  • Original language description

    Submicron particles occurring in the environment are of natural origin, but are also formed by anthropogenic activities as secondary products. The source of these submicron particles are e.g. energy industries, ore processing, cosmetic and pharmaceutical industries, smoking, transportation, etc. Chemical composition of these particles from single sources is not precisely known. Due to their size (<1 mu m) they can be easily inhaled and thus enter deep respiratory tract into the lungs. Depending on their size and chemical composition they may have the ability to induce oxidative stress in cells, which lead to damage to the body eventually. The paper addresses occurrence of unspecified peripheral T-cell lymphoma in a 74-year-old male patient, non-smoker, previously working in metal rollers worker. This case was evaluated from the pathological point of view, together with a detection of submicron particles/clusters in the sample of the tumor tissue. Histologically the tumor was in lung tissue inaccurately bounded with diffusely growing medium sized to large lymphoid elements having nuclei of irregular size and shape and with one or multiple nucleoli with prominent mitotic activity. Dark pigment was also dispersed in the tissue during examination by light microscopy at high magnification under polarized light and also foreign particles probably of metallic character were observed. Experimental method used included scanning electron microscopy with energy dispersive spectroscopy (SEM -EDX) and Raman microspectroscopy. SEM - EDX revealed presence of particles/clusters in sizes <500 nm based mainly on iron. Occurrence of iron particles namely siderite (FeCO3) was confirmed by Raman microspectroscopy. Moreover the tumor tissue was identified to contain carbon black and graphite-based particles.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    DN - Environmental impact on health

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LO1203" target="_blank" >LO1203: Regional Materials Science and Technology Centre - Feasibility Program</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    NANOCON 2015: 7th international conference : proceedings of abstracts

  • ISBN

    978-80-87294-59-8

  • ISSN

  • e-ISSN

  • Number of pages

    558

  • Pages from-to

    553

  • Publisher name

    Tanger

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Oct 14, 2015

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000374708800097