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Light-Propelled Nanorobots for Facial Titanium Implants Biofilms Removal

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F22%3A10250116" target="_blank" >RIV/61989100:27640/22:10250116 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15640/22:73618793 RIV/00216305:26620/22:PU145168 RIV/00216208:11110/22:10444875 RIV/00064165:_____/22:10444875 and 2 more

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/epdf/10.1002/smll.202200708" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1002/smll.202200708</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/smll.202200708" target="_blank" >10.1002/smll.202200708</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Light-Propelled Nanorobots for Facial Titanium Implants Biofilms Removal

  • Original language description

    Titanium miniplates are biocompatible materials used in modern oral and maxillofacial surgery to treat facial bone fractures. However, plate removal is often required due to implant complications. Among them, a biofilm formation on an infected miniplate is associated with severe inflammation, which frequently results in implant failure. In light of this, new strategies to control or treat oral bacterial biofilm are of high interest. Herein, the authors exploit the ability of nanorobots against multispecies bacterial biofilm grown onto facial commercial titanium miniplate implants to simulate pathogenic conditions of the oral microenvironment. The strategy is based on the use of light-driven self-propelled tubular black-TiO2/Ag nanorobots, that unlike traditional ones, exhibit an extended absorption and motion actuation from UV to the visible-light range. The motion analysis is performed separately over UV, blue, and green light irradiation and shows different motion behaviors, including a fast rotational motion that decreases with increasing wavelengths. The biomass reduction is monitored by evaluating LIVE/DEAD fluorescent and digital microscope images of bacterial biofilm treated with the nanorobots under motion/no-motion conditions. The current study and the obtained results can bring significant improvements for effective therapy of infected metallic miniplates by biofilm. (C) 2022 Wiley-VCH GmbH.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    21000 - Nano-technology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Small

  • ISSN

    1613-6810

  • e-ISSN

    1613-6829

  • Volume of the periodical

    18

  • Issue of the periodical within the volume

    22

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    nestrankovano

  • UT code for WoS article

    000792564800001

  • EID of the result in the Scopus database

    2-s2.0-85129573701