Antibacterial Nanomaterials: Mechanisms, Impacts on Antimicrobial Resistance and Design Principles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F23%3A10252869" target="_blank" >RIV/61989100:27640/23:10252869 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15640/23:73620152
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/anie.202217345" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/anie.202217345</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/anie.202217345" target="_blank" >10.1002/anie.202217345</a>
Alternative languages
Result language
angličtina
Original language name
Antibacterial Nanomaterials: Mechanisms, Impacts on Antimicrobial Resistance and Design Principles
Original language description
Antimicrobial resistance (AMR) is one of the biggest threats to the environment and health. AMR rapidly invalidates conventional antibiotics, and antimicrobial nanomaterials have been increasingly explored as alternatives. Interestingly, several antimicrobial nanomaterials show AMR-independent antimicrobial effects without detectable new resistance and have therefore been suggested to prevent AMR evolution. In contrast, some are found to trigger the evolution of AMR. Given these seemingly conflicting findings, a timely discussion of the two faces of antimicrobial nanomaterials is urgently needed. This review systematically compares the killing mechanisms and structure-activity relationships of antibiotics and antimicrobial nanomaterials. We then focus on nano-microbe interactions to elucidate the impacts of molecular initiating events on AMR evolution. Finally, we provide an outlook on future antimicrobial nanomaterials and propose design principles for the prevention of AMR evolution.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10400 - Chemical sciences
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Angewandte Chemie - International Edition
ISSN
1433-7851
e-ISSN
1521-3773
Volume of the periodical
2023
Issue of the periodical within the volume
62
Country of publishing house
DE - GERMANY
Number of pages
26
Pages from-to
"e202217345"
UT code for WoS article
000934438800001
EID of the result in the Scopus database
2-s2.0-85147919108