A general atomically dispersed copper catalyst for C-O, C-N, and C-C bond formation by carbene insertion reactions
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F24%3A10255075" target="_blank" >RIV/61989100:27640/24:10255075 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/abs/pii/S2451929424000834?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S2451929424000834?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chempr.2024.02.021" target="_blank" >10.1016/j.chempr.2024.02.021</a>
Alternative languages
Result language
angličtina
Original language name
A general atomically dispersed copper catalyst for C-O, C-N, and C-C bond formation by carbene insertion reactions
Original language description
The implementation of heterogeneous catalysts in advanced organic synthesis provides basis for the sustainable and cost-effective preparation of pharmaceuticals, agrochemicals, and other structurally complex molecules. Crucial for such applications is the design of appropriate catalytic materials with high selectivity and functional group compatibility. Although many homogeneous catalysts are well known for this purpose, heterogeneous ones, specifically those based on non-noble metals, are scarce. Here, we present the preparation and wide-ranging applications of a specific atomically dispersed copper catalyst for highly selective carbene insertion reactions of diazo compounds with alcohols, phenols, amines, thiols, and N-heterocycles. The optimal catalyst (Cu-NC/Al2O3) contains Al2O3-supported copper-based single atoms coordinated with nitrogen species, which can be conveniently prepared by the pyrolysis of Cu-MOF-303. The resulting catalyst allows for the selective formation of C-O, C-N, and C-C bonds in functionalized and structurally diverse molecules (e.g., complex natural products and drugs), including highly sensitive alkynes and azides. (C) 2024 Elsevier Inc.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10400 - Chemical sciences
Result continuities
Project
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Continuities
O - Projekt operacniho programu
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Chem
ISSN
2451-9308
e-ISSN
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Volume of the periodical
10
Issue of the periodical within the volume
6
Country of publishing house
US - UNITED STATES
Number of pages
13
Pages from-to
1897-1909
UT code for WoS article
001254183200001
EID of the result in the Scopus database
2-s2.0-85189653200