PREVALENCE OF INHERITED THROMBOPHILIA IN PATIENTS WITH SEVERE OVARIAN HYPERSTIMULATION SYNDROME

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F06%3A00003166" target="_blank" >RIV/61989592:15110/06:00003166 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

PREVALENCE OF INHERITED THROMBOPHILIA IN PATIENTS WITH SEVERE OVARIAN HYPERSTIMULATION SYNDROME

Original language description

Background and objective: To determine the prevalence of markers of inherited thrombophilia in patients with severe form of ovarian hyperstimulation syndrome (OHSS) Design and methods: Blood samples were analysed for markers of thrombophilia (mutation offactor V - Leiden, mutation of methylentetrahydrofolat reductase (MTHFR) C677T and mutation of prothrombin G20210A). The study group consisted of women who had undergone controlled ovarian hyperstimulation for IVF complicated by severe OHSS (group A, n= 50). Results were compared with two controls groups - women who underwent ovarian hyperstimulation for IVF without developing OHSS (group B, n = 93) and healthy pregnant women with no history of infertility (group C, n = 196). Results: We have found 7out of 50 patients from group A positive for Leiden mutation (heterozygous) 11 out of 93 from group B (heterozygous), p = 0.71 OR 1.21 (0.39 3.70) and 10 out of 196 from group C (heterozygous), p = 0.03 OR 3.03 (0.97 9.28). Polymorphism o

Czech name

Prevalence vrozené trombofilie u pacientek se závažným ovariálním hyperstimulačním syndromem

Czech description

Prospektivní studie hodnotí význam vrozené trombofilie jako rizikového faktoru pro ovariální hyperstimulační syndrom

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FK - Gynaecology and obstetrics

OECD FORD branch

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Project

<a href="/en/project/NR7810" target="_blank" >NR7810: Relation between thrombophilias and severe ovarian hyperstimulation syndrome</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers

ISSN

1213-8118

e-ISSN

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Volume of the periodical

150

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

289-292

UT code for WoS article

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EID of the result in the Scopus database

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