Small intestinal submukosa (SIS) in the treatment of bulbourethral strictures

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F06%3A00003179" target="_blank" >RIV/61989592:15110/06:00003179 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Small intestinal submukosa (SIS) in the treatment of bulbourethral strictures

Original language description

Introduction & Objectives Anterior urethral strictures that are too long to be excised and re-anastomosed are best treated with substitution urethroplasty using free graft or pedicled skin flaps. Another possibility is to use xenografts. The authors evaluate their experience with small intestinal submucosa (SIS) onlay patch in the treatment of non-resectable anterior urethral strictures from the functional point of view. Material & Methods In year 2003 from January to December SIS was used as an onlay patch in bulbar and penile urethra in 50 patients (45-73, av.56,4). Four layered SIS contains no cells therefore has no risk of rejection. Matrix is commercially available - SURGISIS SLH 4S, Cook Urological Inc. SIS was measured to fit the needed caliberwithout considering shrinkage and sutured in place with running 5-zero polyglactin sutures. The wound was closed in layers and a catheter was left in place for 3 weeks and only removed after radiological evidence of satisfactory healing

Czech name

Submukosa tenkého střeva (SIS) při léčení bulbouretrálních struktur

Czech description

Introduction & Objectives Anterior urethral strictures that are too long to be excised and re-anastomosed are best treated with substitution urethroplasty using free graft or pedicled skin flaps. Another possibility is to use xenografts. The authors evaluate their experience with small intestinal submucosa (SIS) onlay patch in the treatment of non-resectable anterior urethral strictures from the functional point of view. Material & Methods In year 2003 from January to December SIS was used as an onlay patch in bulbar and penile urethra in 50 patients (45-73, av.56,4). Four layered SIS contains no cells therefore has no risk of rejection. Matrix is commercially available - SURGISIS SLH 4S, Cook Urological Inc. SIS was measured to fit the needed caliberwithout considering shrinkage and sutured in place with running 5-zero polyglactin sutures. The wound was closed in layers and a catheter was left in place for 3 weeks and only removed after radiological evidence of satisfactory healing

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FJ - Surgery including transplantology

OECD FORD branch

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Project

<a href="/en/project/NR7764" target="_blank" >NR7764: Acellular collagen matrix for urethral strictures repair</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

European Urology

ISSN

1569-9056

e-ISSN

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Volume of the periodical

5

Issue of the periodical within the volume

2

Country of publishing house

FR - FRANCE

Number of pages

270

Pages from-to

46

UT code for WoS article

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EID of the result in the Scopus database

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