Treatment with atorvastatin reduces serum adipocyte-fatty acid binding protein value in patients with hyperlipidaemia
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F07%3A00003982" target="_blank" >RIV/61989592:15110/07:00003982 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16370/07:00001085
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
Treatment with atorvastatin reduces serum adipocyte-fatty acid binding protein value in patients with hyperlipidaemia
Original language description
Background Adipocyte-fatty acid binding prottein (A-FABP) is a circulating protein expressed in adipocytes and macrophages. Several recent studies deminstrated that A-FABP might be involed in the pathogenesis of metabolic syndrome, particularly in dyslipidaemia, insulin resistance and atherosclerosis. The aim of this study was to investigete the influence of atorvastatin treatment (20 mg day for 3 months) on serum A-FABP value in subjects with hyperlipidaemia. Conclusions In conclusion, our study confirmed in vivo that atorvastatin reduces serum A-FABP by a pleiotropic mechanism and supports the hypothesis that A-FABP is involved in atherosclerotic actions.
Czech name
Léčba atorvastatinem redukuje sérové hodnoty "adipocyte-fatty acid binding" protteinu u pacientů s hyperlipidémií
Czech description
A-FABP je cirkulující protein exprimovaný v adipocytech v makrofázích. Současné studie uvádějí, že A-FABP by mohl mít roli v patogenezi metabolického syndromu, především v rozvoji dyslipidémie, inzulínové rezistence a aterosklerózy.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—
Result continuities
Project
<a href="/en/project/1A8250" target="_blank" >1A8250: Frequency and Distribution of Insulin Resistance as a Risk Factor for Cardiovascular and Metabolic Diseases</a><br>
Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2007
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Clinical Investigation
ISSN
0014-2972
e-ISSN
—
Volume of the periodical
8
Issue of the periodical within the volume
37
Country of publishing house
GB - UNITED KINGDOM
Number of pages
6
Pages from-to
637-642
UT code for WoS article
—
EID of the result in the Scopus database
—