The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A00006173" target="_blank" >RIV/61989592:15110/08:00006173 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/08:#0000358

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

The correlation of serum immunoglobulin free light chain levels and selected biological markers in multiple myeloma

Original language description

Aims: The presented study is aimed at the evaluation of correlation of free light chains serum levels - kappa, lambda and their relation (K/L ratio) and serum levels of selected biological markers in a group of patients with multiple myeloma examined atthe time of the diagnosis. Methods: 102 patients with multiple myeloma were included in this prospective study. Free light chains serum levels were determined by Freelite TM Binding Site system, for determination of serum levels of selected parameters the following methods were used: REA thymidinekinase (TK), RIA (beta2microglobulin), ICTP, PINP, enzymoimmunoassay (sIL-6R, sVCAM-1, sICAM-1, sOPG) and quantitative enzymatic immunoassay (sHGF, sVEGF, sSyndecan-1 (sSyn-1) a sFas). Results: There was founda correlation in the kappa-group of the dominant kappa chain and serum readings of beta2m (r=0,344, p=0,005), TK (r=0,263, p=0,035), ICTP (r=0,402, p=0,001), PINP (r=0,264, p=0,039), sOPG (r=0,328, p=0,028), sSyn-1 (r=0,255, p=0,046) a sF

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

—

Project

<a href="/en/project/NR9500" target="_blank" >NR9500: Angiogenesis, plasma cell kinetics, parameters of microenvironments of bone marrow and bone metabolism in monoclonal gammopathy of undetermined significance and initial phases of multiple myeloma</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers

ISSN

1213-8118

e-ISSN

—

Volume of the periodical

152

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

—

UT code for WoS article

—

EID of the result in the Scopus database

—