Prolonged survival of patients with peripheral T-Cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F09%3A00009474" target="_blank" >RIV/61989592:15110/09:00009474 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/09:00009739

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Prolonged survival of patients with peripheral T-Cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation

Original language description

Background: Nodal peripheral T-cell lymphomas (PTCLs) are infrequent subtypes of non-Hodgkin?s lymphomas.-The WHO classification recognizes three subgroups of nodal PTCL: peripheral T-cell lymphoma not otherwise specified-(PTCL, NOS), anaplastic large cell lymphoma (ALCL) and angioimmunoblastic lymphoma (AIL). The clinical-course is aggressive and despite multiagent chemotherapy, the median survival is about 2 years. Optimal first-line chemotherapy-is not established and the role of high-dose therapy with autologous stem cell support is still controversial.-Aim: To analyze the long-term outcome of PTCL patients treated with intensive first-line chemotherapy with highdose-therapy and autologous transplant consolidation. Method: Sequential chemotherapy protocol consisting of 3 cycles of CHOEP-21-like regimen (PACEBO), 1 cycle-of an ifosfamide and methotrexate-based regimen (IVAM) and a priming regimen with high-dose cytosine arabinoside-(HAM). Consolidation was provided with myeloablativ

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers

ISSN

1213-8118

e-ISSN

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Volume of the periodical

153

Issue of the periodical within the volume

1

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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