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POTENTIAL MARKERS OF INSULIN RESISTANCE IN HEALTHY VS OBESE AND OVERWEIGHT SUBJECTS

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F10%3A10213554" target="_blank" >RIV/61989592:15110/10:10213554 - isvavai.cz</a>

  • Result on the web

    —

  • DOI - Digital Object Identifier

    —

Alternative languages

  • Result language

    angličtina

  • Original language name

    POTENTIAL MARKERS OF INSULIN RESISTANCE IN HEALTHY VS OBESE AND OVERWEIGHT SUBJECTS

  • Original language description

    Background. Insulin resistance can lead to the metabolic syndrome, which may have cardiovascular and metabolic consequences. The study aimed at verifying the serum concentration levels of the adipose tissue proteins adiponectin,adipocyte-fatty acid binding protein (a-FABP) and acylation stimulating protein (ASP), and the potential use of these markers for early diagnosis of insulin resistance. Methods and results. Healthy subjects (Group A, n = 53), overweight subjects (Group B, n = 29) and obese subjects(Group C, n = 51) were studied. The subjects were selected based on clinical and laboratory findings. Conclusions. The concentrations of all studied markers were different in the healthy subjects as compared to the overweight or obese ones. Adiponectinproved to be a good indicator of insulin sensitivity, the low concentration of which could signal the initial stage of insulin resistance. A-FABP proved to be a prominent marker of ?adiposity? in association with the development of insul

  • Czech name

    —

  • Czech description

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Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

    —

Result continuities

  • Project

    <a href="/en/project/NT11098" target="_blank" >NT11098: Epidemiological study of adipose tissue proteins importance in relation to insulin resistance</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers

  • ISSN

    1213-8118

  • e-ISSN

    —

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    154(3)

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    5

  • Pages from-to

    —

  • UT code for WoS article

    —

  • EID of the result in the Scopus database

    —

Similar results(10)

Adipocyte fatty acid binding protein and C-reactive protein levels as indicators of insulin resistance development.Inflammation as a Risk Factor for the Development of Insulin ResistanceAdipocyte fatty acid binding protein in a Caucasian population: a new marker of metabolic syndrome?