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Detection and clinical importance of minimal residual disease in patients with lung cancer - a pilot study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F11%3A10224852" target="_blank" >RIV/61989592:15110/11:10224852 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Detection and clinical importance of minimal residual disease in patients with lung cancer - a pilot study

  • Original language description

    Lung cancer is one of the leading causes of cancer death and has become an increasingly urgent worldwide health problem (incidence in men 34.01100 000, in women 13.61100 000; mortality in men 29.3/100 000, in women 11.0/1 00 000) (globocan.iarc. fr, 2008). Mortality is increasingly associated with distant metastases development. The minimal residual disease (MRD) in solid tumours means the presence of occult tumour cells in the body of a patient who has undergone curative surgery and has no timher clinical signs of the disease. These isolated occult tumour cells are considered to be the precursors of micrometastases. The MRD testing in lung cancer patients can eliminate complicated surgical procedures in patients with systemic molecular dissemination of the disease and can improve the prognosis. The aim of our pilot study was to establish and validate PCR-based method for MRD testing in lung cancer using different molecular markers.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    New Frontiers in the Research of PhD Students. Conference of Medical Schools.

  • ISBN

    978-80-260-0922-1

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    12-15

  • Publisher name

    Univerzita Karlova

  • Place of publication

    Praha

  • Event location

    Hradec Králové

  • Event date

    Nov 10, 2011

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article