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Influence of age and gender on the pharmacodynamic parameters of rocuronium during total intravenous anesthesia

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F11%3A33115963" target="_blank" >RIV/61989592:15110/11:33115963 - isvavai.cz</a>

  • Alternative codes found

    RIV/00098892:_____/11:#0000109

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Influence of age and gender on the pharmacodynamic parameters of rocuronium during total intravenous anesthesia

  • Original language description

    Aims. To compare the pharmacodynamics of 0.6 mg kg-1 rocuronium in young and older patients of both genders during total intravenous anesthesia. Methods. Following local ethics committee approval and informed consent, patients scheduled for surgery undertotal intravenous anesthesia (propofol/sufentanil) were divided into 4 study groups: 37 males aged 20-40, 40 males aged 60-75 yrs, 43 females aged 20-40 and 38 females aged 60-75 yrs. Neuromuscular block following rocuronium (0.6 mg kg-1) was monitored:train-of-four [TOF] stimulation of the ulnar nerve at 15-s intervals, EMG of the adductor pollicis muscle. The onset time (from application of rocuronium to maximum depression of T1), clinical duration (from application to 25% recovery of T1), and timeto full spontaneous recovery (from application to TOF-ratio ? 0.9) were determined for each patient.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS9618" target="_blank" >NS9618: Epidemiological study of prediction of difficult intubation</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Biomedical Papers-Olomouc

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    155

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    8

  • Pages from-to

    233-240

  • UT code for WoS article

  • EID of the result in the Scopus database