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Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F12%3A33140469" target="_blank" >RIV/61989592:15110/12:33140469 - isvavai.cz</a>

  • Alternative codes found

    RIV/00098892:_____/12:#0000343

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects

  • Original language description

    Some findings support the role of serum adipocyte fatty acidbinding protein (A-FABP) as a key pro-inflammatory mediator that links obesity with cardiovascular diseases.The aim of the study was to evaluate the association of A-FABP with endothelial/hemostatic markers, plasminogen activator inhibitor-1, tissue-plasminogen activator, soluble intercellular cell adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in asymptomatic dyslipidemic subjects. We examined 105 dyslipidemic patients without clinical manifestation of atherosclerosis and 50 normolipidemic healthy subjects, who served as a control group. Except of endothelial/hemostatic markers, anthropometric and lipid parameters, markers of insulin resistance and inflammation were assessed. Conclusion: Study displayed an independent positive association of A-FABP with vWF in clinically asymptomatic dyslipidemic subjects. Contribution of A-FABP in the process of endothelial dysfunction could help to explain the role of abe

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FB - Endocrinology, diabetology, metabolism, nutrition

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS10284" target="_blank" >NS10284: Dyslipidemia and prehypertension - association of dyslipidemic phenotypes with prevalence of prehypertension. Association of prehypertension with markers of insulin resistance, inflammation, endothelial dysfunction and subclinical atherosclerosis.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Neuroendocrinology Letters

  • ISSN

    0172-780X

  • e-ISSN

  • Volume of the periodical

    33

  • Issue of the periodical within the volume

    suppl. 2

  • Country of publishing house

    SE - SWEDEN

  • Number of pages

    6

  • Pages from-to

    26-31

  • UT code for WoS article

  • EID of the result in the Scopus database