Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F12%3A33140469" target="_blank" >RIV/61989592:15110/12:33140469 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/12:#0000343
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Relationship between serum adipocyte fatty acid-binding protein and endothelial/hemostatic markers in dyslipidemic subjects
Original language description
Some findings support the role of serum adipocyte fatty acidbinding protein (A-FABP) as a key pro-inflammatory mediator that links obesity with cardiovascular diseases.The aim of the study was to evaluate the association of A-FABP with endothelial/hemostatic markers, plasminogen activator inhibitor-1, tissue-plasminogen activator, soluble intercellular cell adhesion molecule-1 and soluble vascular cell adhesion molecule-1 in asymptomatic dyslipidemic subjects. We examined 105 dyslipidemic patients without clinical manifestation of atherosclerosis and 50 normolipidemic healthy subjects, who served as a control group. Except of endothelial/hemostatic markers, anthropometric and lipid parameters, markers of insulin resistance and inflammation were assessed. Conclusion: Study displayed an independent positive association of A-FABP with vWF in clinically asymptomatic dyslipidemic subjects. Contribution of A-FABP in the process of endothelial dysfunction could help to explain the role of abe
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FB - Endocrinology, diabetology, metabolism, nutrition
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NS10284" target="_blank" >NS10284: Dyslipidemia and prehypertension - association of dyslipidemic phenotypes with prevalence of prehypertension. Association of prehypertension with markers of insulin resistance, inflammation, endothelial dysfunction and subclinical atherosclerosis.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroendocrinology Letters
ISSN
0172-780X
e-ISSN
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Volume of the periodical
33
Issue of the periodical within the volume
suppl. 2
Country of publishing house
SE - SWEDEN
Number of pages
6
Pages from-to
26-31
UT code for WoS article
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EID of the result in the Scopus database
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