Occult tumour cells in peritoneal lavage are a negative prognostic factor in pancreatic cancer
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33139210" target="_blank" >RIV/61989592:15110/13:33139210 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/13:#0000564
Result on the web
<a href="http://biomed.papers.upol.cz/pdfs/bio/2013/03/05.pdf" target="_blank" >http://biomed.papers.upol.cz/pdfs/bio/2013/03/05.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Occult tumour cells in peritoneal lavage are a negative prognostic factor in pancreatic cancer
Original language description
Aims: The aim of this study was to test the hypothesis that occult tumour cells in peritoneal lavage may be a negative prognostic factor in pancreatic adenocarcinoma. Methods: Real-time RT-PCR analysis of CEA, EGFR and hTERT transcript levels was used toidentify occult tumour cells in peritoneal lavage samples from 96 pancreatic cancer patients. Results: We found significant association between CEA expression levels in peritoneal lavage and the clinical stage. We also found that EGFR transcript levelswere higher in peritoneal lavage samples from patients with high grade tumours than in samples from patients with low grade tumours. Detection of CEA and/or EGFR occult tumour cell markers in the peritoneal lavage was associated with significantly shorter overall survival for the patients and an increased hazard ratio for disease recurrence. Conclusions: The results demonstrate that the presence of occult tumour cells in peritoneal lavage is a negative prognostic factor for survival in p
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers-Olomouc
ISSN
1213-8118
e-ISSN
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Volume of the periodical
157
Issue of the periodical within the volume
3
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
6
Pages from-to
233-238
UT code for WoS article
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EID of the result in the Scopus database
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