Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33143448" target="_blank" >RIV/61989592:15110/13:33143448 - isvavai.cz</a>
Alternative codes found
RIV/68378050:_____/13:00423021 RIV/60461373:22330/13:43895397 RIV/60461373:22810/13:43895397
Result on the web
<a href="http://dx.doi.org/10.1016/j.steroids.2012.11.016" target="_blank" >http://dx.doi.org/10.1016/j.steroids.2012.11.016</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.steroids.2012.11.016" target="_blank" >10.1016/j.steroids.2012.11.016</a>

Result language
angličtina
Original language name
Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors
Original language description
There were synthesized new types of ribbon type steroidal dimers derived from three types of steroidal skeletons (cholic acid, etienic acid, estrone) using CuI catalyzed 1, 3-dipolar cycloaddition reaction. Steroid parts of the molecular ''ribbons'' arelinked by heterocyclic moiety, namely by 2,6-bis((1H-1,2,3-triazol- 1-yl)-methyl)pyridine. Compounds synthesized possess different cytotoxic and hormone receptor modulating activities.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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