Effects of oral administration of Lonicera caerulea berries on UVB-induced damage in SKH-1 mice. A pilot study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33144121" target="_blank" >RIV/61989592:15110/13:33144121 - isvavai.cz</a>
Result on the web
<a href="http://pubs.rsc.org/en/content/articlelanding/2013/pp/c3pp50120e#!divAbstract" target="_blank" >http://pubs.rsc.org/en/content/articlelanding/2013/pp/c3pp50120e#!divAbstract</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c3pp50120e" target="_blank" >10.1039/c3pp50120e</a>

Result language
angličtina
Original language name
Effects of oral administration of Lonicera caerulea berries on UVB-induced damage in SKH-1 mice. A pilot study
Original language description
Solar ultraviolet radiation is a major environmental factor that has serious adverse effects on the structure and function of the skin. Although the UVB waveband (295-315 nm) represents only 5-10% of incoming UV light, it is very damaging to the skin. The aim of this study was to investigate the effect of Lonicera caerulea berries on UVB-induced damage to SKH-1 hairless mice. Mice were fed a L. caerulea berry-enriched diet (10%, w/w) for 14 days before a single UVB (1000 mJ cm(-2)) treatment. Effects onhealth status, antioxidant enzyme activity and expression, and DNA damage were evaluated. The bioavailability of L. caerulea phenolic components was also assessed. We found that feeding with L. caerulea berries prevented a decrease in catalase activityand stimulated NADPH quinone oxidoreductase-1, heme oxygenase-1, and gamma-glutamylcysteine synthetase catalytic and modulatory subunit expression in UVB exposed mice. Administration of the L. caerulea berry-enriched diet led to an increa
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CE - Biochemistry
OECD FORD branch
—

Project
<a href="/en/project/GP303%2F07%2FP314" target="_blank" >GP303/07/P314: Photoprotective effects of natural plant phenolics in vitro and in vivo</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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