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The response of osteoblast-like SaOS-2 cells to modified titanium surfaces.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33144554" target="_blank" >RIV/61989592:15110/13:33144554 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.quintpub.com/journals/omi/abstract.php?article_id=13597" target="_blank" >http://www.quintpub.com/journals/omi/abstract.php?article_id=13597</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.11607/jomi.3039" target="_blank" >10.11607/jomi.3039</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    The response of osteoblast-like SaOS-2 cells to modified titanium surfaces.

  • Original language description

    Purpose: To study the effects of different chemically modified titanium surfaces on the proliferation, differentiation, adhesion and apoptosis of osteoblast-like SaOS-2 cells. Materials and Methods: In this work, six different titanium materials: i) glazed, ii) unglazed, iii) unglazed and alkali etched, iv) unglazed sand blasted acid and alkali etched, v) unglazed and coated with ZrN, vi) unglazed sand blasted and acid etched, were compared with cells on plastic. The production of alkaline phosphatase (ALP), tumor necrosis factor alpha (TNF-a), matrix metalloproteinase-2 (MMP-2) and the expression of adhesion proteins (integrin a3b1, vinculin) were evaluated using ELISA methods. Finally, the apoptosis of cells was analyzed by flow cytometry. Results: The most significant differences were found for unglazed sand blasted acid and alkali etched titanium disc in comparison with cells on plastic. The proliferation was decreased after 96 h. The production of TNF-a was decreased after 24 h as

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Oral Maxillofacial Implants

  • ISSN

    0882-2786

  • e-ISSN

  • Volume of the periodical

    28

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    1386-1394

  • UT code for WoS article

  • EID of the result in the Scopus database