C-13-methacetin breath test in the evaluation of disease severity in patients with liver cirrhosis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F13%3A33147367" target="_blank" >RIV/61989592:15110/13:33147367 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11120/13:43907709 RIV/68407700:21460/13:00217378 RIV/00064173:_____/13:N0000018
Result on the web
<a href="http://dx.doi.org/10.5507/bp.2012.114" target="_blank" >http://dx.doi.org/10.5507/bp.2012.114</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2012.114" target="_blank" >10.5507/bp.2012.114</a>

Result language
angličtina
Original language name
C-13-methacetin breath test in the evaluation of disease severity in patients with liver cirrhosis
Original language description
Aims: The non-invasive 13C-methacetin (13C-MBT) breath test has been proposed as a measure of metabolic liver function that improves the diagnostic efficacy of serologic and biochemical tests in assessing hepatic functional capacity and liver disease severity, The goal of this study was to establish the clinical utility of this test in quantifying hepatic metabolic function in patients with liver cirrhosis of varying severity and to compare 13C-MBT measurements with the AST/ALT ratio, APRI score, and other routine liver tests. Methods: Routine liver function tests including serum bilirubin, aspartate aminotransferase activity (AST), alanine aminotransferase (ALT), AST/ALT ratio, the APRI score, the percentage of dose rate (PDR) and cumulative percentage of dose rate (CPDR) of the 13C-MBT were evaluated in 52 cirrhotic patients of alcohol etiology (Child-Pugh A/B/C 10/28/14) and 37 healthy controls. Results: The 13C-MBT differed significantly between healthy controls and cirrhotic patie
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FE - Other fields of internal medicine
OECD FORD branch
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Project
<a href="/en/project/ED0030%2F01%2F01" target="_blank" >ED0030/01/01: Biomedicine for regional development and human resources</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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