2-[18F]fluoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33145755" target="_blank" >RIV/61989592:15110/14:33145755 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/14:#0000660
Result on the web
<a href="http://dx.doi.org/10.3109/10428194.2013.802313" target="_blank" >http://dx.doi.org/10.3109/10428194.2013.802313</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3109/10428194.2013.802313" target="_blank" >10.3109/10428194.2013.802313</a>

Result language
angličtina
Original language name
2-[18F]fluoro-2-deoxy- D -glucose positron emission tomography/ computed tomography examination in patients with chronic lymphocytic leukemia may reveal Richter transformation
Original language description
The signifi cance of positron emission tomography/computed tomography (PET/CT) in chronic lymphocytic leukemia (CLL) has not yet been systematically studied. This prospective study was aimed at assessing the benefi t of PET/CT in patients with newly diagnosed or relapsed CLL and Richter transformation (RT). PET/CT examination was performed in 23 patients with newly diagnosed disease, 13 with relapsed disease and eight with suspected or histopathologically confi rmed RT. In all patients, the maximum standardized uptake value (SUV max ) was calculated. The median SUV max was 3.4 (range: 1.5 – 6.3) and 3.1 (range: 1.2 – 5.9) in newly diagnosed and relapsed patients, respectively. The median SUV max of patients with suspected or confi rmed RT reached 16.5 (range: 7.2 – 25.3), a value diff erent from that of the previous groups ( p 0.001). 2-[18F]fl uoro- 2-deoxy- D -glucose ( 18 F-FDG) PET/CT revealed infl ammatory lesions in seven patients (16%) and synchronous tumors in two newly diagnosed patients. 18 F-FDG PET/CT may be a benefi cial imaging method when used in individuals with CLL and suspected RT.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30205 - Hematology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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