Incidence of unlicensed and off-label prescription in children

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33147836" target="_blank" >RIV/61989592:15110/14:33147836 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/14:#0000664

Result on the web

<a href="http://dx.doi.org/10.1186/1824-7288-40-12" target="_blank" >http://dx.doi.org/10.1186/1824-7288-40-12</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/1824-7288-40-12" target="_blank" >10.1186/1824-7288-40-12</a>

Result language

angličtina

Original language name

Incidence of unlicensed and off-label prescription in children

Original language description

Many common drugs have not been licensed for use in children. This study evaluated the incidence of unlicensed and off-label prescriptions at the Department of Pediatrics during a period of six months. A total of 8,559 prescriptions for 4,282 children were processed. Off-label and unlicensed prescriptions were found in 9.01% and 1.26% of all prescriptions, respectively. Unlicensed prescriptions were significantly more common in boys (1.5%) than in girls (1.0%) (p = 0.037). There was no significant difference between off-label prescriptions in boys (9.0%) and in girls (9.1%) (p = 0.89). The prescription of unlicensed drugs was significantly more frequent in school age children (p { 0.0001). The most commonly prescribed unlicensed drugs were angiotensin-converting enzyme inhibitors; among off-label drugs, antihistamines and bronchodilators. This study shows that the incidence of unlicensed and off-label drug prescriptions in our patients is not as high as in other studies.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FR - Pharmacology and apothecary chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Italian Journal of Pediatrics

ISSN

1824-7288

e-ISSN

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Volume of the periodical

40

Issue of the periodical within the volume

12

Country of publishing house

IT - ITALY

Number of pages

6

Pages from-to

1-6

UT code for WoS article

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EID of the result in the Scopus database

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