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Chemical Properties and Biological Activities of Cyclopentenediones: A Review

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33149191" target="_blank" >RIV/61989592:15110/14:33149191 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11160/14:10282273

  • Result on the web

    <a href="http://www.eurekaselect.com/120771/article" target="_blank" >http://www.eurekaselect.com/120771/article</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.2174/1389557514666140306130207" target="_blank" >10.2174/1389557514666140306130207</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Chemical Properties and Biological Activities of Cyclopentenediones: A Review

  • Original language description

    Cyclopentenediones (CPDs) are secondary metabolites of higher plants, fungi, algae, cyanobacteria and bacteria. A common denominator of CPDs is the cyclopent-4-ene 1,3-dione skeleton (1), which is modified by several functional groups. The heterogeneityof these substitutions is reflected in around one hundred CPDs reported to date. Most of the derivatives were isolated primarily from plant sources. Synthetic analogues were then prepared with new biological activities and more interesting pharmacological potential. Antifungal substances called coruscanones (2, 3) are the most studied of the CPDs. Other intensely investigated CPDs include lucidone (4), linderone (5), asterredione (6), involutone (7), nostotrebin 6 (8), TX-1123 (9), G2201-C (10), madindolines (11, 12) and many others. In addition to antibacterial and antifungal effects, a broad spectrum of biological activities for CPDs has been reported in the past two decades, especially anti-inflammatory, cytostatic and specific enzym

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CE - Biochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP207%2F10%2F2048" target="_blank" >GAP207/10/2048: Chiral Quinazoline Alkaloids: Potential Prototypes of Novel Antiasthmatics and Organocatalysts</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Mini-Reviews in Medicinal Chemistry

  • ISSN

    1389-5575

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    10

  • Pages from-to

    322-331

  • UT code for WoS article

  • EID of the result in the Scopus database