Intrathecal synthesis in particular types of multiple sclerosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33150095" target="_blank" >RIV/61989592:15110/14:33150095 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/14:#0000712
Result on the web
<a href="http://dx.doi.org/10.5507/bp.2012.054" target="_blank" >http://dx.doi.org/10.5507/bp.2012.054</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2012.054" target="_blank" >10.5507/bp.2012.054</a>
Alternative languages
Result language
angličtina
Original language name
Intrathecal synthesis in particular types of multiple sclerosis
Original language description
The aim of this study was to determine whether there were any differences in intrathecal synthesis of immunoglobulin G (IgG) (IgG index) and number of oligoclonal bands (OCB) among particular types of multiple sclerosis (MS). METHODS: 120 cerebrospinal fluid (CSF) samples were examined from 29 clinically isolated syndrome (CIS) patients and 91 MS patients (77 patients with relapsing-remitting MS (RR), 6 patients with primary progressive course of the disease (PP) and 8 patients in secondary progression(SP)); mean age = 42 years (range = 18 to 70 years). Albumin and IgG in serum and CSF was evaluated using nephelometry; an albumin quotient (CSF albumin/serum albumin), an IgG quotient (CSF IgG/serum IgG) and an IgG index (IgG quotient / albumin quotient) were then calculated. OCB were assessed using isoelectric focusing (IEF) on agarose gel, followed by immunoblotting. All patients were evaluated using the Kurtzke Expanded Disability Status Scale (EDSS). RESULTS: No statistically signif
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biomedical Papers-Olomouc
ISSN
1213-8118
e-ISSN
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Volume of the periodical
158
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
3
Pages from-to
124-126
UT code for WoS article
000338627400020
EID of the result in the Scopus database
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