Primary cilia in gastrointestinal stromal tumors.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F14%3A33150534" target="_blank" >RIV/61989592:15110/14:33150534 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11150/14:10227254 RIV/00179906:_____/14:10227254 RIV/27283933:_____/14:N0000027
Result on the web
<a href="http://dx.doi.org/10.4149/neo_2014_039" target="_blank" >http://dx.doi.org/10.4149/neo_2014_039</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.4149/neo_2014_039" target="_blank" >10.4149/neo_2014_039</a>
Alternative languages
Result language
angličtina
Original language name
Primary cilia in gastrointestinal stromal tumors.
Original language description
The primary cilium is a solitary, sensory, non-motile microtubule-based structure that arises from the centrosome and is projected from the surface of most human cells. The objective of the current pilot study was to conduct an investigation of presenceand frequency of cilia in gastrointestinal stromal tumors (GIST).The presence of primary cilia in GIST was evaluated in 9 patients, including 8 primary tumors and 1 liver metastasis. In 2 patients the presence of primary cilia was evaluated not only in the primary tumor, but also in recurrence: in 1 patient in recurrence without previous treatment with imatinib and in 1 patient in recurrence after treatment with imatinib. The primary cilia of GIST cells were immunofluorescently stained with primary monoclonal anti-acetylated tubulin alpha antibody and cell nuclei with DAPI.We observed 9985 nuclei of cells of GISTs and 425 primary cilia in total. The median of frequency of primary cilia in cells of GISTs in all examined samples was 4.26%
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neoplasma
ISSN
0028-2685
e-ISSN
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Volume of the periodical
61
Issue of the periodical within the volume
3
Country of publishing house
SK - SLOVAKIA
Number of pages
4
Pages from-to
305-308
UT code for WoS article
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EID of the result in the Scopus database
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