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Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (Mll-ME2) fusion gene

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33154989" target="_blank" >RIV/61989592:15110/15:33154989 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.cancergen.2015.09.004" target="_blank" >http://dx.doi.org/10.1016/j.cancergen.2015.09.004</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.cancergen.2015.09.004" target="_blank" >10.1016/j.cancergen.2015.09.004</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (Mll-ME2) fusion gene

  • Original language description

    We describe a unique case of a woman with acute myeloid leukemia with a new, previously undescribed translocation, t(11;18)(q23;q21.2), affecting the KMT2A (MLL) gene and resulting in an KMT2A(MLL)-ME2 fusion. This disease occurred secondarily followingchemotherapy for a different acute myeloid leukemia with the recurrent genetic abnormality inv(16)(p13.1;q22). The secondary leukemia was treated with intensive chemotherapy without allogeneic hematopoietic cell transplantation. Complete remission lasting more than 10 years has been achieved with concurrent and sustained remission of the primary leukemia.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Cancer Genetics and Cytogenetics

  • ISSN

    0165-4608

  • e-ISSN

  • Volume of the periodical

    208

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    610-614

  • UT code for WoS article

  • EID of the result in the Scopus database