Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (Mll-ME2) fusion gene
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33154989" target="_blank" >RIV/61989592:15110/15:33154989 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.cancergen.2015.09.004" target="_blank" >http://dx.doi.org/10.1016/j.cancergen.2015.09.004</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cancergen.2015.09.004" target="_blank" >10.1016/j.cancergen.2015.09.004</a>
Alternative languages
Result language
angličtina
Original language name
Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (Mll-ME2) fusion gene
Original language description
We describe a unique case of a woman with acute myeloid leukemia with a new, previously undescribed translocation, t(11;18)(q23;q21.2), affecting the KMT2A (MLL) gene and resulting in an KMT2A(MLL)-ME2 fusion. This disease occurred secondarily followingchemotherapy for a different acute myeloid leukemia with the recurrent genetic abnormality inv(16)(p13.1;q22). The secondary leukemia was treated with intensive chemotherapy without allogeneic hematopoietic cell transplantation. Complete remission lasting more than 10 years has been achieved with concurrent and sustained remission of the primary leukemia.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FD - Oncology and haematology
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cancer Genetics and Cytogenetics
ISSN
0165-4608
e-ISSN
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Volume of the periodical
208
Issue of the periodical within the volume
12
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
610-614
UT code for WoS article
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EID of the result in the Scopus database
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