Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33155977" target="_blank" >RIV/61989592:15110/15:33155977 - isvavai.cz</a>

Alternative codes found

RIV/65269705:_____/15:00063015 RIV/00179906:_____/15:10318038 RIV/00843989:_____/15:E0104813 RIV/00216224:14110/15:00087435

Result on the web

<a href="http://dx.doi.org/10.1002/ajh.23910" target="_blank" >http://dx.doi.org/10.1002/ajh.23910</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ajh.23910" target="_blank" >10.1002/ajh.23910</a>

Result language

angličtina

Original language name

Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia

Original language description

IgM monoclonal gammopathies are a group of diseases characterized by increased level of IgM immunoglobulin produced by one clone of B cells. These diseases range trom benign (monoclonal gammopathy ot undetermined significance, MGUS) to malignant, such asWaldenstrom macroglobulinemia (WM) or to a lesser extent multiple myeloma (MM) [1,2]. The criteria that differentiate WM from IgM-MGUS are based on the extent of bone marrow (BM) involvement, amount of serum concentration of the M-proicin, presence or absence of symptomatic disease or more recently, MYD88 (L265P) or CXCR4 mutations [3-6]. Despite that, new criteria for the differential diagnosis between these conditions are still needed, circulating microRNAs (miRNAs) being one of them. Circulating miRNAs are present in different body fluids; they reflect physiological or pathologi cal conditions and can be used tor patient classification [7,8]. Thus, we aimed to investigate the ability of serum miRNAs to distinguish WM from IgM-MGUS a

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

American Journal of Hematology

ISSN

0361-8609

e-ISSN

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Volume of the periodical

90

Issue of the periodical within the volume

3

Country of publishing house

US - UNITED STATES

Number of pages

2

Pages from-to

51-52

UT code for WoS article

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EID of the result in the Scopus database

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