First Report of the Global SYMPLICITY Registry on the Effect of Renal Artery Denervation in Patients With Uncontrolled Hypertension

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33157676" target="_blank" >RIV/61989592:15110/15:33157676 - isvavai.cz</a>

Result on the web

<a href="http://hyper.ahajournals.org/content/65/4/766.long" target="_blank" >http://hyper.ahajournals.org/content/65/4/766.long</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.05010" target="_blank" >10.1161/HYPERTENSIONAHA.114.05010</a>

Result language

angličtina

Original language name

First Report of the Global SYMPLICITY Registry on the Effect of Renal Artery Denervation in Patients With Uncontrolled Hypertension

Original language description

This study aimed to assess the safety and effectiveness of renal denervation using the Symplicity system in real-world patients with uncontrolled hypertension (NCT01534299). The Global SYMPLICITY Registry is a prospective, open-label, multicenter registry. Office and 24-hour ambulatory blood pressures (BPs) were measured. Change from baseline to 6 months was analyzed for all patients and for subgroups based on baseline office systolic BP, diabetic status, and renal function; a cohort with severe hypertension (office systolic pressure, GREATER-THAN OR EQUAL TO160 mm Hg; 24-hour systolic pressure, GREATER-THAN OR EQUAL TO135 mm Hg; and GREATER-THAN OR EQUAL TO3 antihypertensive medication classes) was also included. The analysis included protocol-definedsafety events. Six-month outcomes for 998 patients, including 323 in the severe hypertension cohort, are reported. Mean baseline office systolic BP was 163.5+-24.0 mm Hg for all patients and 179.3+-16.5 mm Hg for the severe cohort; the c

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FA - Cardiovascular diseases including cardio-surgery

OECD FORD branch

—

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Hypertension

ISSN

0073-425X

e-ISSN

—

Volume of the periodical

65

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

9

Pages from-to

766-774

UT code for WoS article

—

EID of the result in the Scopus database

—