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Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33158377" target="_blank" >RIV/61989592:15110/15:33158377 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/15:00456001 RIV/61989592:15310/15:33158377

  • Result on the web

    <a href="http://dx.doi.org/10.1255/ejms.1350" target="_blank" >http://dx.doi.org/10.1255/ejms.1350</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1255/ejms.1350" target="_blank" >10.1255/ejms.1350</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging

  • Original language description

    The lateral lipid distribution in eye lenses of three human donors were studied by matrix-assisted laser desorption ionization imaging mass spectrometry using a high mass resolution. By using exact mass measurements this study shows the relationship between the aging process and the number of lipids detected as well as between aging and the abundance of products derived from sphingomyelins by hydrolysis. Variable lipid composition was also observed in the nuclear, barrier, or cortex regions of the lens samples. This is the first study that suggests the distribution of lysolipids as a potential biomarker panel for the aging of human lens tissue.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CB - Analytical chemistry, separation

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Mass Spectrometry

  • ISSN

    1469-0667

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    297-303

  • UT code for WoS article

    000364826200022

  • EID of the result in the Scopus database