Electrocatalytic monitoring of methylglyoxal-mediated protein glycation: pilot results with solubilized Na/K ATPase transmembrane protein

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F16%3A33159409" target="_blank" >RIV/61989592:15110/16:33159409 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Electrocatalytic monitoring of methylglyoxal-mediated protein glycation: pilot results with solubilized Na/K ATPase transmembrane protein
Original language description
Anotace: In this contribution, a first sensing strategy for protein glycation is proposed, based on protein electroactivity measurement. Concretely, the label-free method proposed is based on the application of a constant-current chronopotentiometric stripping analysis at Hg-containing electrodes. The glycation process was monitored as the decrease in the electrocatalytic protein signal, peak H, observed at highly negative potentials, which was previously ascribed to a catalytic hydrogen evolution reaction. Using this method, water fully soluble (bovine serum albumin, human serum albumin and lysozyme) and poorly soluble membrane (Na+/K+- ATPase) proteins were investigated.
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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