DatSCAN In Differential Diagnostics of Lewy Body Disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F16%3A33160800" target="_blank" >RIV/61989592:15110/16:33160800 - isvavai.cz</a>

Result on the web

<a href="http://eds.a.ebscohost.com/eds/pdfviewer/pdfviewer?sid=ae5a4c1e-2ad7-49b3-8a44-8c98feca532c%40sessionmgr4006&vid=1&hid=4203" target="_blank" >http://eds.a.ebscohost.com/eds/pdfviewer/pdfviewer?sid=ae5a4c1e-2ad7-49b3-8a44-8c98feca532c%40sessionmgr4006&vid=1&hid=4203</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

DatSCAN In Differential Diagnostics of Lewy Body Disease

Original language description

Differential diagnosis between Lewy body disease and Alzheimer's disease might be difficult because of similarities of clinical symptoms in both neurodegenerative diseases. DatSCAN is a modern functional neuroimmaging method which differentiates between this similar diseases and helps in correct treatment strategy. We report our positive experience with DatSCAN in differentiating Lewy body disease from Alzheimer's disease. This is a case report of a woman with Lewy body disease, initially diagnosed as Alzheimer's disease. DatSCAN neuroimmaging method was used in differential diagnosis of dementia. Memory impairment, impaired activities of daily living, sleep and behavioral disturbances were present in our case. Donepezil was well tolerated, but haloperidol administration was followed by development of severe dystonia. DatSCAN showed deficient dopaminergic presynaptic transport in substantia nigra and striatum. This finding is typical for Lewy body disease not for Alzheimer's disease. DatSCAN neuroimmaging is a suitable method for differentiating Lewy body disease from Alzheimer's disease. Deficient dopaminergic presynaptic transport in substantia nigra and striatum is typical for Lewy body disease.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FQ - Public health system, social medicine

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Archives of Iranian Medicine

ISSN

1029-2977

e-ISSN

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Volume of the periodical

19

Issue of the periodical within the volume

6

Country of publishing house

IR - IRAN, ISLAMIC REPUBLIC OF

Number of pages

4

Pages from-to

449-452

UT code for WoS article

000378109300012

EID of the result in the Scopus database

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