Heterogeneity of Aberrant O-Glycosylation of IgA1 in IgA Nephropathy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F16%3A33162268" target="_blank" >RIV/61989592:15110/16:33162268 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-4-431-55588-9" target="_blank" >http://dx.doi.org/10.1007/978-4-431-55588-9</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-4-431-55588-9" target="_blank" >10.1007/978-4-431-55588-9</a>
Alternative languages
Result language
angličtina
Original language name
Heterogeneity of Aberrant O-Glycosylation of IgA1 in IgA Nephropathy
Original language description
IgA nephropalhy, a frequent cause of end-stage renal disease, is an autoimmune disease wherein immune complexes consisting of IgA1 with galaclose-deficient O-glycans and anti-glycan autoantibodies deposit in the glomeruli and induce renal injury. Serum IgA1 has three to six clustered O-glycans, some of which may be deficient in galactose and thus expose terminal or sialylated N-acetylgalactoseamine. Patients with IgAN usually have elevated serum levels of Gd-lgA1. The mechanism involved in production of Gd-lgA1 is not fully understood.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
EC - Immunology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Pathogenesis and treatment in IgA Nephropathy
ISBN
978-4-431-55587-2
Number of pages of the result
16
Pages from-to
53-68
Number of pages of the book
342
Publisher name
Springer Japan KK
Place of publication
Tokio
UT code for WoS chapter
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