Clonality of Bacterial Pathogens Causing Hospital-Acquired Pneumonia.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F16%3A33162756" target="_blank" >RIV/61989592:15110/16:33162756 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs00284-016-1058-0" target="_blank" >https://link.springer.com/article/10.1007%2Fs00284-016-1058-0</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00284-016-1058-0" target="_blank" >10.1007/s00284-016-1058-0</a>

Result language
angličtina
Original language name
Clonality of Bacterial Pathogens Causing Hospital-Acquired Pneumonia.
Original language description
Hospital-acquired pneumonia (HAP) is one of the most serious complications in patients staying in intensive care units. This multicenter study of Czech patients with HAP aimed at assessing the clonality of bacterial pathogens causing the condition. Bacterial isolates were compared using pulsed-field gel electrophoresis. Included in this study were 330 patients hospitalized between May 1, 2013 and December 31, 2014 at departments of anesthesiology and intensive care medicine of four big hospitals in the Czech Republic. A total of 531 bacterial isolates were obtained, of which 267 were classified as etiological agents causing HAP. Similarity or identity was assessed in 231 bacterial isolates most frequently obtained from HAP patients. Over the study period, no significant clonal spread was noted. Most isolates were unique strains, and the included HAP cases may therefore be characterized as mostly endogenous. Yet there were differences in species and potential identical isolates between the participating centers. In three hospitals, Gram-negative bacteria (Enterobacteriaceae and Pseudomonas aeruginosa) prevailed as etiological agents, and Staphylococcus aureus was most prevalent in the fourth center.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Project
<a href="/en/project/NT14263" target="_blank" >NT14263: Identifying agents of early-onset and late-onset nosocomial pneumonia in patients in intensive care through genetic analysis of bacterial DNA and determination of their distribution.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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