Characteristics and risk profile of psoriasis patients included in the Czech national registry BIOREP and a comparison with other registries.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73580405" target="_blank" >RIV/61989592:15110/17:73580405 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/17:10359114 RIV/00216208:11120/17:43912926 RIV/00216208:11140/17:10359114 RIV/00064173:_____/17:N0000066 and 4 more

Result on the web

<a href="http://dx.doi.org/10.1111/ijd.13543" target="_blank" >http://dx.doi.org/10.1111/ijd.13543</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/ijd.13543" target="_blank" >10.1111/ijd.13543</a>

Result language

angličtina

Original language name

Characteristics and risk profile of psoriasis patients included in the Czech national registry BIOREP and a comparison with other registries.

Original language description

Background BIOREP is a Czech registry of psoriatic patients on biological treatment in a clinical setting. We describe the characteristics of patients with psoriasis at the time of enrollment and present comparisons with published data from other national registries. Methods We analyzed the cohort of patients treated with biologics between May 2005 and May 2015. Demographic data, previous therapies, comorbidities, and severity of psoriasis were compared with data from other registries – DERMBIO, BIOBADADERM, BADBIR, and PSOBEST. Results A total of 1412 psoriatic patients initiating biological treatment were included with a predominance of males (63.4%). The mean patient age was 50.2 years, and approximately 70.5% of patients were either overweight or obese. The mean baseline Psoriasis Area and Severity Index was 19.8, and the Dermatology Life Quality Index was 16.6. More than one-third of patients (41.0%) reported a history of psoriatic arthritis, and a high proportion of patients (49.5%) with cardiovascular risk factors (hypertension [35.2%], hyperlipidemia [27.7%], diabetes mellitus [11.4%], coronary heart disease [4.9%], and obesity [15.2%]) were observed. Most of the patients had been previously treated with phototherapy (85.4%), acitretin (74.0%), methotrexate (65.7%), or cyclosporine (53.1%). Conclusion BIOREP is one of the first registries of patients with psoriasis treated with biologics in Central and Eastern Europe. Our results found a similar or higher prevalence of comorbidities, long disease duration, and high impact on the quality of life among patients included in Western European registries.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30216 - Dermatology and venereal diseases

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Dermatology

ISSN

0011-9059

e-ISSN

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Volume of the periodical

56

Issue of the periodical within the volume

4

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

428-434

UT code for WoS article

000397580500023

EID of the result in the Scopus database

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