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Galloylation of polyphenols alters their biological activity.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73580610" target="_blank" >RIV/61989592:15110/17:73580610 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/17:00476070

  • Result on the web

    <a href="http://www.sciencedirect.com/science/article/pii/S0278691517301886" target="_blank" >http://www.sciencedirect.com/science/article/pii/S0278691517301886</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.fct.2017.04.021" target="_blank" >10.1016/j.fct.2017.04.021</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Galloylation of polyphenols alters their biological activity.

  • Original language description

    Polyphenols form one of the largest groups of natural compounds and possess a wide range of biological properties. These activities can be influenced by the galloyl moiety within their structures. A multitude of galloylated polyphenolic compounds occurs in nature, but galloylated phenols are also produced synthetically to influence their biological properties. This review provides a comprehensive summary of current knowledge about natural (galloylated catechins, theaflavins and proanthocyanidins, penta-O-galloyl-β-d-glucose, gallotannins, ellagitannins, ellagic acid and flavonols) and semisynthetic gallates with a focus on their biological activity and toxicity issues. The effects of tea catechins (epicatechin, epigallocatechin, epicatechin gallate, and epigallocatechin gallate) and semisynthetic galloyl esters of the flavonolignans silybin and 2,3-dehydrosilybin from the milk thistle (Silybum marianum) on angiogenesis were used as examples of the structure-activity relationship (SAR) study.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Food and Chemical Toxicology

  • ISSN

    0278-6915

  • e-ISSN

  • Volume of the periodical

    105

  • Issue of the periodical within the volume

    July

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    18

  • Pages from-to

    223-240

  • UT code for WoS article

    000403625000024

  • EID of the result in the Scopus database