Metabolic Osteopathy in Late-onset celiac disease

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73580895" target="_blank" >RIV/61989592:15110/17:73580895 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-319-31169-2_20" target="_blank" >http://dx.doi.org/10.1007/978-3-319-31169-2_20</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-319-31169-2_20" target="_blank" >10.1007/978-3-319-31169-2_20</a>

Result language
angličtina
Original language name
Metabolic Osteopathy in Late-onset celiac disease
Original language description
Chapter describes two cases of late onset coeliac disease with development of severe osteopathy characterized by osteomalatia, which was the leading symptom of the illness. Metabolic osteopathy in adult patients is one of the potential manifestations of celiac sprue (CS), also called gluten-sensitive enteropathy. CS is a lifelong intolerance of prolamin contained in crops (gliadin – gluten fraction in wheat, secalin in rye, hordein in barley, etc.) [1]; CS is a common disease widely distributed worldwide, with a characteristic mucosal lesion of the proximal small intestine, associated with nutrient malabsorption. Mucosal lesions range from the initial lymphocytic infiltration up to total atrophy of the resorption epithelium of the small intestine. Histological changes are assessed by means of the Marsh histological criteria for evaluation of the extent of lymphocytic infiltration, glandular crypts, and small intestinal villi (0–4 scale [2–4]).
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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