The role of keratinocytes in inflammation

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73583198" target="_blank" >RIV/61989592:15110/17:73583198 - isvavai.cz</a>

Result on the web

<a href="https://ac.els-cdn.com/S1214021X17300741/1-s2.0-S1214021X17300741-main.pdf?_tid=c230a7c4-f530-11e7-a3c3-00000aab0f26&acdnat=1515497722_504653d9236c6a9c780eba5109671f53" target="_blank" >https://ac.els-cdn.com/S1214021X17300741/1-s2.0-S1214021X17300741-main.pdf?_tid=c230a7c4-f530-11e7-a3c3-00000aab0f26&acdnat=1515497722_504653d9236c6a9c780eba5109671f53</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jab.2017.05.003" target="_blank" >10.1016/j.jab.2017.05.003</a>

Result language

angličtina

Original language name

The role of keratinocytes in inflammation

Original language description

he epidermis is the external layer of the skin and is composed mainly of keratinocytes. Therefore, keratinocytes play an indispensable role as inherent constituents of the skin barrier in physical defenses against environmental threats. Keratinocytes also exert an active protective role against invasion by pathogens. This competency is of particular importance when physical defenses fail as a consequence of skin injury. During the inflammatory phase of healing, keratinocytes act as immuno-modulators, managing inflammation via a rigorously coordinated network of inflammatory cascades, triggered by keratinocyte-receptor communication with the surroundings in a paracrine and autocrine manner. This review summarizes current understandings of the coordinated inflammatory network and focuses on recent progress regarding the role of keratinocytes in early phases of skin wound healing.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

<a href="/en/project/LO1304" target="_blank" >LO1304: Support of suistainability of the Institute of Molecular and Translational Medicine</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Volume of the periodical

15

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

11

Pages from-to

169-179

UT code for WoS article

000408062200002

EID of the result in the Scopus database

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