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Analogs of biologically active compounds IX. Synthesis of several new uracil and pteridine 6-azaanalogs based on cyclization of arylhydrazones derived from mesoxalic acid

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F17%3A73583774" target="_blank" >RIV/61989592:15110/17:73583774 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15310/17:73583774

  • Result on the web

    <a href="http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p010.123" target="_blank" >http://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.p010.123</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.24820/ark.5550190.p010.123" target="_blank" >10.24820/ark.5550190.p010.123</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Analogs of biologically active compounds IX. Synthesis of several new uracil and pteridine 6-azaanalogs based on cyclization of arylhydrazones derived from mesoxalic acid

  • Original language description

    A series of 5C and 5N substituted 3-oxo-2-phenyl-1,2,4-triazine-6-carbonitriles and 8-imino-2-arylpyrimido[4,5-e][1,2,4]triazine-3,6(2H,5H)-diones (6-aryl-6-azapteridines) are described via a cyclocondensation reaction from the corresponding aryliminohydrazones with CDI. The required aryliminohydrazones were obtained from the starting compound – malononitrile. These prepared compounds were tested for cytotoxic activity on cancer cell lines.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

    <a href="/en/project/LO1304" target="_blank" >LO1304: Support of suistainability of the Institute of Molecular and Translational Medicine</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Arkivoc

  • ISSN

    1551-7004

  • e-ISSN

  • Volume of the periodical

    2017

  • Issue of the periodical within the volume

    v

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    12

  • Pages from-to

    129-140

  • UT code for WoS article

    000418768100012

  • EID of the result in the Scopus database