All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Benzoxazole Derivatives as Promising Antitubercular Agents

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F18%3A73591160" target="_blank" >RIV/61989592:15110/18:73591160 - isvavai.cz</a>

  • Alternative codes found

    RIV/61989592:15310/18:73591160

  • Result on the web

    <a href="http://dx.doi.org/10.1002/slct.201800631" target="_blank" >http://dx.doi.org/10.1002/slct.201800631</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1002/slct.201800631" target="_blank" >10.1002/slct.201800631</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Benzoxazole Derivatives as Promising Antitubercular Agents

  • Original language description

    Tuberculosis (TB) is an infectious disease caused predominantly by bacillus Mycobacterium tuberculosis (MTB). The increasing prevalence of multidrug-resistant MTB necessitates the discovery and development of alternative drugs against tuberculosis with a new mechanism of action. Over the past years, several benzoxazole derivatives have been synthesized and screened for their biological activity. Interestingly, some of them had promising antitubercular activity. Despite that, none of the benzoxazole derivatives has entered the phase of the preclinical hit-to-lead optimization step in anti-TB research. In this review, we are summarizing recently published articles that evaluate the potency of benzoxazole heterocycle in the development of novel anti-TB agents and outlined the future aspects of this promising heterocycle.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10401 - Organic chemistry

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ChemistrySelect

  • ISSN

    2365-6549

  • e-ISSN

  • Volume of the periodical

    3

  • Issue of the periodical within the volume

    17

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    10

  • Pages from-to

    4653-4662

  • UT code for WoS article

    000431625900013

  • EID of the result in the Scopus database

    2-s2.0-85046677486