Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73598857" target="_blank" >RIV/61989592:15110/19:73598857 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0039128X18302113?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0039128X18302113?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.steroids.2018.11.007" target="_blank" >10.1016/j.steroids.2018.11.007</a>

Result language
angličtina
Original language name
Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins
Original language description
In recent years, the interest in metabolic-type and natural products drugs that have the ability to activate plastic processes in various organs and tissues, improve the energy status of their cellular systems, and thereby improve the body resistance to various adverse factors, increased significantly. According to the results of the experimental and clinical studies, one of the most effective drugs in this area could be “Ecdisten” (Five Stars Laboratory, Bulgaria) developed on the basis of the natural ecdysterone (20E) contained in various plant sources such as Leuzea carthamoides alias Rhaponticum carthamoides, Rhaponticum integrifolium, Silene brahuica, Ajuga turkestanica etc. by the Institute of the Chemistry of Plant Substances (Tashkent, Republic of Uzbekistan), and the “Ekdifit” preparation developed at the International Research and Production Holding “Phytochemistry” (Karaganda, Republic of Kazakhstan), which is the sum of the extracs of Serratula coronata and contains 20E as the main active component and additional amounts of ecdysteroids and flavonoids [1], [2], [3], [4].
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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