Severity of panic disorder, adverse events in childhood, dissociation, self-stigma and comorbid personality disorders Part 2: Therapeutic effectiveness of a combined cognitive behavioural therapy and pharmacotherapy in treatment-resistant inpatients

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73601199" target="_blank" >RIV/61989592:15110/19:73601199 - isvavai.cz</a>

Alternative codes found

RIV/00098892:_____/19:N0000183

Result on the web

<a href="https://www.nel.edu/userfiles/articlesnew/1586541996_40_6_kolek_271-pdf.pdf" target="_blank" >https://www.nel.edu/userfiles/articlesnew/1586541996_40_6_kolek_271-pdf.pdf</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Severity of panic disorder, adverse events in childhood, dissociation, self-stigma and comorbid personality disorders Part 2: Therapeutic effectiveness of a combined cognitive behavioural therapy and pharmacotherapy in treatment-resistant inpatients

Original language description

OBJECTIVES: A combination of antidepressants with the cognitive-behavioural therapy showed effectiveness in treatment-resistant patients with panic disorder. This prospective study intended to establish how childhood adverse experiences, self-stigma, dissociation, and severity of psychopathology influence the effectiveness of combined cognitive-behavioural therapy and pharmacotherapy in patients with treatment-resistant panic disorder. METHODS: One hundred and ten patients were included into the study and one hundred five subjects finished the study. After admission, the subjects were assessed during the first two days of hospitalization. Rating scales were administered before the beginning of the cognitive behavioural therapy (measurement-1) and at the end of the treatment which was after six weeks (measurement-2). Patients with panic disorder were treated using a combination of group cognitivebehavioural therapy and antidepressants. The usual antidepressant dosage range was used. Before admission to intensive cognitive behavioural therapy program, the patients were unsuccessfully treated by antidepressants for minimum 3 months, which defined them as pharmacoresistant. RESULTS: Hospitalized pharmacoresistant patients with panic disorder improved significantly throughout the 6-week intensive CBT program in all measurements that assessed the overall severity of the disorder, the degree of general anxiety and depression and the severity of specific symptoms of panic disorder and agoraphobia.

Czech name

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Czech description

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Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

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OECD FORD branch

50102 - Psychology, special (including therapy for learning, speech, hearing, visual and other physical and mental disabilities);

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

NEUROENDOCRINOLOGY LETTERS

ISSN

0172-780X

e-ISSN

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Volume of the periodical

40

Issue of the periodical within the volume

6

Country of publishing house

SE - SWEDEN

Number of pages

13

Pages from-to

271-283

UT code for WoS article

000521944800004

EID of the result in the Scopus database

2-s2.0-85082780292