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Evaluation and management of toxicity of cytoreductive surgery/hyperthermic intraperitoneal chemotherapy: the initial experience of a single centre study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73596865" target="_blank" >RIV/61989592:15110/20:73596865 - isvavai.cz</a>

  • Alternative codes found

    RIV/00098892:_____/20:N0000220

  • Result on the web

    <a href="https://biomed.papers.upol.cz/artkey/bio-202003-0012_evaluation-and-management-of-toxicity-of-cytoreductive-surgery-hyperthermic-intraperitoneal-chemotherapy-the-i.php" target="_blank" >https://biomed.papers.upol.cz/artkey/bio-202003-0012_evaluation-and-management-of-toxicity-of-cytoreductive-surgery-hyperthermic-intraperitoneal-chemotherapy-the-i.php</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2019.035" target="_blank" >10.5507/bp.2019.035</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Evaluation and management of toxicity of cytoreductive surgery/hyperthermic intraperitoneal chemotherapy: the initial experience of a single centre study

  • Original language description

    Background: Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment modality for peritoneal surface malignancies with efficacy reported in many trials. Discrepancies, however, in the indication criteria, the extent of the surgical procedure, HIPEC regimens and toxicity evaluation represent a problem when comparing this method with other therapeutic modalities. Methods: We describe the initial experience with CRS/HIPEC using different chemotherapy regimens (oxaliplatin, cisplatin, mitomycin C and doxorubicin) at the Comprehensive Oncology Centre Olomouc. Results: A perioperative mortality of 2% and perioperative morbidity of 11%, according to Clavien-Dindo were observed. Interestingly, all these patients underwent HIPEC with oxaliplatin 460 mg/m2. The median duration of admission to hospital was 6 days in the intensive care unit (range 2-28 days) and 7 days in the surgical ward (range 1-21 days).

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BIOMEDICAL PAPERS-OLOMOUC

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    164

  • Issue of the periodical within the volume

    3

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    7

  • Pages from-to

    300-306

  • UT code for WoS article

    000595645600012

  • EID of the result in the Scopus database

    2-s2.0-85091167853