Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73601239" target="_blank" >RIV/61989592:15110/20:73601239 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s00408-020-00353-2" target="_blank" >https://link.springer.com/article/10.1007/s00408-020-00353-2</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00408-020-00353-2" target="_blank" >10.1007/s00408-020-00353-2</a>
Alternative languages
Result language
angličtina
Original language name
Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis
Original language description
Cystic fibrosis (CF) is caused by a defect in the CF transmembrane conductance regulator (CFTR) protein, which functions as a chloride channel regulator. Dysfunction of the CFTR protein results in pancreatic insufficiency, intestinal obstruction, male infertility, and severe pulmonary complications which are the main cause of morbidity and mortality in CF patients [1]. CF-related symptoms worsen with age, and patients usually experience a progressive decline in lung function with every additional year of living. This increases the risk of complications related to CF lung disease [2].
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/EF16_019%2F0000868" target="_blank" >EF16_019/0000868: Molecular, cellular and clinical approach to healthy ageing</a><br>
Continuities
—
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
LUNG
ISSN
0341-2040
e-ISSN
—
Volume of the periodical
198
Issue of the periodical within the volume
3
Country of publishing house
DE - GERMANY
Number of pages
11
Pages from-to
459-469
UT code for WoS article
000527497500001
EID of the result in the Scopus database
2-s2.0-85083509082