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Sarcopenia in Metastatic Renal Cell Carcinoma Patients Treated with Cabozantinib

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73602635" target="_blank" >RIV/61989592:15110/20:73602635 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14110/20:00116254 RIV/00216208:11110/20:10416834 RIV/00064190:_____/20:N0000008 RIV/00209805:_____/20:00078442

  • Result on the web

    <a href="https://link.springer.com/article/10.1007%2Fs11523-020-00744-8" target="_blank" >https://link.springer.com/article/10.1007%2Fs11523-020-00744-8</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s11523-020-00744-8" target="_blank" >10.1007/s11523-020-00744-8</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Sarcopenia in Metastatic Renal Cell Carcinoma Patients Treated with Cabozantinib

  • Original language description

    Background Sarcopenia is common in advanced cancer and correlates with poor performance status, increased risk of treatment-related toxicity, and shortened survival. Inhibitors of the vascular endothelial growth factor pathway have been associated with development or deterioration of sarcopenia. Objective To assess the prevalence and impact of sarcopenia on survival in patients with metastatic renal cell carcinoma (mRCC) treated with cabozantinib, a novel, highly potent multikinase inhibitor. Patients and Methods Patients treated with cabozantinib for mRCC progressing on other targeted therapies with available computed tomography (CT) scans acquired at the time of initiation of cabozantinib and on the first restaging were evaluated retrospectively. Muscle mass was assessed based on striated muscle area at the level of the third lumbar vertebra.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Targeted Oncology

  • ISSN

    1776-2596

  • e-ISSN

  • Volume of the periodical

    15

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    FR - FRANCE

  • Number of pages

    7

  • Pages from-to

    673-679

  • UT code for WoS article

    000555352100001

  • EID of the result in the Scopus database

    2-s2.0-85089013138