Prescriptive Reference Standards of Third-Trimester Cerebroplacental Ratio and Its Physiological Determinants
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F20%3A73606932" target="_blank" >RIV/61989592:15110/20:73606932 - isvavai.cz</a>
Result on the web
<a href="https://www.karger.com/Article/Abstract/508366" target="_blank" >https://www.karger.com/Article/Abstract/508366</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1159/000508366" target="_blank" >10.1159/000508366</a>
Alternative languages
Result language
angličtina
Original language name
Prescriptive Reference Standards of Third-Trimester Cerebroplacental Ratio and Its Physiological Determinants
Original language description
Objective:To construct valid reference standards reflecting optimal cerebroplacental ratio and to explore its physiological determinants.Methods:A cohort of 391 low-risk pregnancies of singleton pregnancies of nonmalformed fetuses without maternal medical conditions and with normal perinatal outcomes was created. Doppler measurements of the middle cerebral artery and umbilical artery were performed at 24-42 weeks. Reference standards were produced, and the influence of physiological determinants was explored by nonparametric quantile regression. The derived standards were validated in a cohort of 200 low-risk pregnancies.Results:Maternal body mass index was significantly associated with the 5th centile of the cerebroplacental ratio. For each additional unit of body mass index, the 5th centile was on average 0.014 lower. The derived 5th, 10th, and 50th centiles selected in the validation cohort were 5, 9.5, and 51% of the measurements.Conclusions:This study provides methodologically sound prescriptive standards and suggests that maternal body mass index is a determinant of a cutoff commonly used for decision-making.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30214 - Obstetrics and gynaecology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
FETAL DIAGNOSIS AND THERAPY
ISSN
1015-3837
e-ISSN
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Volume of the periodical
47
Issue of the periodical within the volume
10
Country of publishing house
CH - SWITZERLAND
Number of pages
8
Pages from-to
757-764
UT code for WoS article
000579154200005
EID of the result in the Scopus database
2-s2.0-85088388613