Changes in serum lipid levels during pregnancy in women with gestational diabetes. A narrative review.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73609144" target="_blank" >RIV/61989592:15110/21:73609144 - isvavai.cz</a>
Result on the web
<a href="https://biomed.papers.upol.cz/pdfs/bio/2021/01/02.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2021/01/02.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.5507/bp.2021.009" target="_blank" >10.5507/bp.2021.009</a>
Alternative languages
Result language
angličtina
Original language name
Changes in serum lipid levels during pregnancy in women with gestational diabetes. A narrative review.
Original language description
We review current knowledge on lipid metabolism changes during pregnancy with special focus on changes in gestational diabetes. In physiological pregnancy, total plasma cholesterol, triglyceride and HDL-cholesterol level rises, the atherogenic index (LDL-cholesterol / HDL-cholesterol remains unchanged. Compared with healthy women, women with GDM show more pronounced signs of mixed dyslipidaemia – increased levels of triglyceride, changes in cholesterol and lipoprotein concentrations with a shift towards greater small dense LDL subtractions, which is typical for insulin resistance states. Dyslipidaemia, particularly hypertriglyceridemia, is thought to be one of the key drivers of foetal macrosomia and that is why measurements of plasma lipids may be valuable in detecting the metabolic abnormality in GDM and in predicting foetal outcome. Dyslipidaemia in GDM is seen as proatherogenic and potentially harmful for the baby and therefore it should be monitored more carefully.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30202 - Endocrinology and metabolism (including diabetes, hormones)
Result continuities
Project
<a href="/en/project/NV18-01-00139" target="_blank" >NV18-01-00139: Gestational diabetes mellitus - contribution of entero-insular axis hormones, selected adipokines and gut microbiota to its different phenotypes</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BIOMEDICAL PAPERS-OLOMOUC
ISSN
1213-8118
e-ISSN
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Volume of the periodical
165
Issue of the periodical within the volume
1
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
5
Pages from-to
8-12
UT code for WoS article
000629606300002
EID of the result in the Scopus database
2-s2.0-85103178793