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Changes in serum lipid levels during pregnancy in women with gestational diabetes. A narrative review.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73609144" target="_blank" >RIV/61989592:15110/21:73609144 - isvavai.cz</a>

  • Result on the web

    <a href="https://biomed.papers.upol.cz/pdfs/bio/2021/01/02.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2021/01/02.pdf</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.5507/bp.2021.009" target="_blank" >10.5507/bp.2021.009</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Changes in serum lipid levels during pregnancy in women with gestational diabetes. A narrative review.

  • Original language description

    We review current knowledge on lipid metabolism changes during pregnancy with special focus on changes in gestational diabetes. In physiological pregnancy, total plasma cholesterol, triglyceride and HDL-cholesterol level rises, the atherogenic index (LDL-cholesterol / HDL-cholesterol remains unchanged. Compared with healthy women, women with GDM show more pronounced signs of mixed dyslipidaemia – increased levels of triglyceride, changes in cholesterol and lipoprotein concentrations with a shift towards greater small dense LDL subtractions, which is typical for insulin resistance states. Dyslipidaemia, particularly hypertriglyceridemia, is thought to be one of the key drivers of foetal macrosomia and that is why measurements of plasma lipids may be valuable in detecting the metabolic abnormality in GDM and in predicting foetal outcome. Dyslipidaemia in GDM is seen as proatherogenic and potentially harmful for the baby and therefore it should be monitored more carefully.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30202 - Endocrinology and metabolism (including diabetes, hormones)

Result continuities

  • Project

    <a href="/en/project/NV18-01-00139" target="_blank" >NV18-01-00139: Gestational diabetes mellitus - contribution of entero-insular axis hormones, selected adipokines and gut microbiota to its different phenotypes</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    BIOMEDICAL PAPERS-OLOMOUC

  • ISSN

    1213-8118

  • e-ISSN

  • Volume of the periodical

    165

  • Issue of the periodical within the volume

    1

  • Country of publishing house

    CZ - CZECH REPUBLIC

  • Number of pages

    5

  • Pages from-to

    8-12

  • UT code for WoS article

    000629606300002

  • EID of the result in the Scopus database

    2-s2.0-85103178793