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Morphometric analysis of Hofbauer cells in normal placenta and chorioamnionitis in humans

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73611240" target="_blank" >RIV/61989592:15110/21:73611240 - isvavai.cz</a>

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/full/10.1111/ahe.12644" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1111/ahe.12644</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/ahe.12644" target="_blank" >10.1111/ahe.12644</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Morphometric analysis of Hofbauer cells in normal placenta and chorioamnionitis in humans

  • Original language description

    Hofbauer cells are macrophages residing in the stroma of placental villi and play a number of roles during normal pregnancy, as well as pathological conditions. A comparative morphometric analysis of Hofbauer cells, in particular to investigate the number of cells, their size and shape in samples of normal placenta from 1st trimester and term and with chorioamnionitis was performed. Tissue samples were immunostained for CD206 antigen and evaluated using ImageJ software. We detected significant changes in number and morphology of HBCs between normal placenta and placenta with chorioamnionitis samples. In chorioamnionitis, the cells were unevenly distributed within the villi, generally present in higher numbers, larger and more elongated than those in normal 1st trimester and term placenta. We could speculate that changed morphology of HBCs in chorioamnionitis can be associated with an alteration in their anti-inflammatory function.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10601 - Cell biology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    ANATOMIA HISTOLOGIA EMBRYOLOGIA

  • ISSN

    0340-2096

  • e-ISSN

  • Volume of the periodical

    50

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    8

  • Pages from-to

    396-403

  • UT code for WoS article

    000597846100001

  • EID of the result in the Scopus database

    2-s2.0-85097394250