Benefits of 18F-FET PET in preoperative assessment of glioma heterogeneity demonstrated in two case reports

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F21%3A73615875" target="_blank" >RIV/61989592:15110/21:73615875 - isvavai.cz</a>
Result on the web
<a href="https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2021-4-9/benefits-of-18f-fet-pet-in-preoperative-assessment-of-glioma-heterogeneity-demonstrated-in-two-case-reports-128182" target="_blank" >https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2021-4-9/benefits-of-18f-fet-pet-in-preoperative-assessment-of-glioma-heterogeneity-demonstrated-in-two-case-reports-128182</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.48095/cccsnn2021405" target="_blank" >10.48095/cccsnn2021405</a>

Result language
angličtina
Original language name
Benefits of 18F-FET PET in preoperative assessment of glioma heterogeneity demonstrated in two case reports
Original language description
Dear Editor, Magnetic resonance imaging is still considered the gold standard of diagnostic algorithms in gliomas. However, especially in gliomas with atypical enhancement patterns, PET could improve evaluation by monitoring processes such as cell proliferation,membrane biosynthesis, and glucose consumption [1]. Radiolabeled amino acids are frequently used PET tracers due to their high signal-to-noise ratio. In contrast to glucose derivatives, the uptake of amino acids in inflammatory cells is lower, which makes themmore specific for tumor detection [2]. Moreover, amino acids are accumulated in malignant cells owing to increased expression of type L amino acid transporters in tumor vasculature [3]. Additionally, the counter-transport system A is overexpressed in neoplastic cells and seems to correlate positively with tumor cell growth rate [4].
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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