Temperature sensation in Parkinson's disease measured by quantitative sensory testing: a single-center, case-control study.

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F23%3A73609506" target="_blank" >RIV/61989592:15110/23:73609506 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/23:10157893
Result on the web
<a href="https://www.tandfonline.com/doi/full/10.1080/00207454.2021.1991922" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/00207454.2021.1991922</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/00207454.2021.1991922" target="_blank" >10.1080/00207454.2021.1991922</a>

Result language
angličtina
Original language name
Temperature sensation in Parkinson's disease measured by quantitative sensory testing: a single-center, case-control study.
Original language description
Background The pathophysiology of abnormal temperature sensation in Parkinson's disease (PD) remains unclear. Abnormal thermal detection does not seem to depend on the dopaminergic deficit, suggesting that other systems play a role in these changes, probably both central and peripheral. Methods We measured thermal detection thresholds (TDT) using quantitative sensory testing (QST) in 28 patients with PD and compared them with 15 healthy controls. Results Of 28 patients, 21% had increased TDT according to the normative data. TDT were higher on the dominant side. No correlation between TDT and disease duration, severity of motor impairment, and dopaminergic therapy was observed. 50% of the patients had difficulty differentiating between warm and cold stimuli, as TDT were within the normal range in most of these patients. Conclusions Twenty-one percent of the patients in our study had increased TDT according to the normative data. Abnormal thermal detection was more pronounced on the dominant side. Abnormal differentiation between the thermal stimuli suggest impaired central processing of thermal information
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30210 - Clinical neurology

Project
<a href="/en/project/EF16_019%2F0000868" target="_blank" >EF16_019/0000868: Molecular, cellular and clinical approach to healthy ageing</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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