COVID-19 reduces cardiorespiratory fitness even months after a mild to moderate acute phase: a retrospevtive cohort study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F23%3A73619495" target="_blank" >RIV/61989592:15110/23:73619495 - isvavai.cz</a>

Result on the web

<a href="https://www.tandfonline.com/doi/full/10.1080/23744235.2023.2228408" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/23744235.2023.2228408</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/23744235.2023.2228408" target="_blank" >10.1080/23744235.2023.2228408</a>

Result language

angličtina

Original language name

COVID-19 reduces cardiorespiratory fitness even months after a mild to moderate acute phase: a retrospevtive cohort study

Original language description

Background: COVID-19 survivors may experience long-term health problems, including deterioration of cardiorespiratory fitness (CRF), as demonstrated by several cross-sectional studies that compared the results of cardiopulmonary exercise tests (CPET) performed only after COVID-19 with predicted values. This study aimed to analyze a change in CRF between repeated CPETs in response to suffered COVID-19. Methods: A total of 127 healthcare workers (HCWs; mean age 55.7 years) underwent two CPETs with a mean interval of 762 days. Forty HCWs suffered from COVID-19 (mild to moderate severity) in the interim (321 days before the second CPET), and 87 HCWs formed a control group. Mixed-effects regression with multiple adjustment and interaction terms was used for two response variables – maximum oxygen uptake (VO2 max) and power output. Results: Between both CPETs, mean VO2 max decreased statistically significantly in the COVID-19 subgroup (by 3.12mL/kg/min, p¼.034) and insignificantly in controls (by 0.56 mL/kg/min, p¼.412). The proportion of HCWs achieving predicted VO2 max decreased from 75.9% to 59.5% (p¼.161) in COVID-19 survivors, while it increased from 73.8% to 81% (p¼.274) in controls. COVID-19 (b ¼ 0.66, p¼.014) and body mass index (b ¼ 0.49, p&lt;.001) were independent negative predictors of VO2 max change. COVID-19 was not associated with a change in power output. Conclusions: On the basis of repeated CPETs, COVID-19 significantly, albeit rather modestly, reduces CRF almost one year after infection. The reduction persists even after the acute phase with mild or moderate severity.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30305 - Occupational health

Project

<a href="/en/project/NU22-A-105" target="_blank" >NU22-A-105: Predicitve biomarkers of therapeutic response on COVID-19 therapy</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Infectious Diseases

ISSN

2374-4235

e-ISSN

2374-4243

Volume of the periodical

55

Issue of the periodical within the volume

10

Country of publishing house

NO - NORWAY

Number of pages

11

Pages from-to

684-693

UT code for WoS article

001021407100001

EID of the result in the Scopus database

2-s2.0-85164174482