Preoperative nutritional support in patients undergoing pancreatic surgery affects PREPARE score accuracy
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F23%3A73621909" target="_blank" >RIV/61989592:15110/23:73621909 - isvavai.cz</a>
Alternative codes found
RIV/00098892:_____/23:10158285
Result on the web
<a href="https://www.frontiersin.org/articles/10.3389/fsurg.2023.1275432/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fsurg.2023.1275432/full</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3389/fsurg.2023.1275432" target="_blank" >10.3389/fsurg.2023.1275432</a>
Alternative languages
Result language
angličtina
Original language name
Preoperative nutritional support in patients undergoing pancreatic surgery affects PREPARE score accuracy
Original language description
Background: This study aimed to validate the accuracy of the PreoperativePancreatic Resection (PREPARE) risk score in pancreatic resection patients.Patients and methods: This prospective study included 216 patients who underwentpancreatic resection between January 2015 and December 2018. All patients in ourcohort with weight loss or lack of appetite received dietary advice and preoperativeoral nutritional supplementation (600 kcal/day). Demographic, clinicopathological,operative, and postoperative data were collected prospectively. The PREPAREscore and the predicted risk of major complications were computed for eachpatient. Differences in major postoperative complications were analyzed using amultivariate Cox proportional hazards regression model. The predicted andobserved risks of major complications were tested using the C-statistic.Results: The study included 216 patients [117 men (54.2%)] with a median age of65.0 (30.0–83.0) years. The majority of patients were classified as AmericanSociety of Anesthesiologists (ASA)’ Physical Status score II (N = 164/216; 75.9%)and as “low risk” PREPARE score (N = 185/216; 85.6%) before the surgery. Only 4(1.9%) patients were malnourished, with albumin levels of less than 3.5 g/dl. Themost common type of pancreatic resection was a pylorus-preservingpancreaticoduodenectomy (N = 122/216; 56.5%). Major morbidity and 30-daymortality rates were 11.1% and 1.9%, respectively. The type of surgical procedure(hazard ratio [HR]: 3.849; 95% confidence interval [CI]: 1.208–12.264) and ASAscore (HR: 3.089; 95% CI: 1.067–8.947) were significantly associated with theincidence of major postoperative complications in multivariate analysis. Thereceiver operating characteristic curve was 0.657 for incremental values and0.559 for risk categories, indicating a weak predictive model.Conclusion: The results of the present study suggest that the PREPARE risk scorehas low accuracy in predicting the risk of major complications in patients withconsistent preoperative nutritional support. This limits the use of PREPARE riskscore in future preoperative clinical routines.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30212 - Surgery
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Frontiers in Surgery
ISSN
2296-875X
e-ISSN
2296-875X
Volume of the periodical
10
Issue of the periodical within the volume
November 2023
Country of publishing house
CH - SWITZERLAND
Number of pages
7
Pages from-to
1275432
UT code for WoS article
001104281200001
EID of the result in the Scopus database
999